Wanting to escape a broken relationship and a stressful career in the UK, Dr. Ruby Walker (Amrita Acharia, Game of Thrones) takes a job in India. Ruby ends up at the overcrowded and underfunded Good Karma Hospital run by the formidable Dr. Lydia Fonseca (Amanda Redman, New Tricks). After the initial culture shock, Ruby learns to deal with the hospital’s demanding schedule and many eccentric inhabitants, including her enigmatic colleague, Dr. Gabriel Varma (James Floyd, Falcón), and nearby beach bar owner, Greg (Neil Morrissey, Line of Duty).

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